Padé Approximants and Exact Two-locus Sampling Distributions By

نویسندگان

  • PAUL A. JENKINS
  • YUN S. SONG
چکیده

For population genetics models with recombination, obtaining an exact, analytic sampling distribution has remained a challenging open problem for several decades. Recently, a new perspective based on asymptotic series has been introduced to make progress on this problem. Specifically, closed-form expressions have been derived for the first few terms in an asymptotic expansion of the two-locus sampling distribution when the recombination rate ρ is moderate to large. In this paper, a new computational technique is developed for finding the asymptotic expansion to an arbitrary order. Computation in this new approach can be automated easily. Furthermore, it is proved here that only a finite number of terms in the asymptotic expansion is needed to recover (via the method of Padé approximants) the exact two-locus sampling distribution as an analytic function of ρ; this function is exact for all values of ρ ∈ [0,∞). It is also shown that the new computational framework presented here is flexible enough to incorporate natural selection.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Padé Approximants and Exact Two-locus Sampling Distributions.

For population genetics models with recombination, obtaining an exact, analytic sampling distribution has remained a challenging open problem for several decades. Recently, a new perspective based on asymptotic series has been introduced to make progress on this problem. Specifically, closed-form expressions have been derived for the first few terms in an asymptotic expansion of the two-locus s...

متن کامل

Constructing Approximate and Exact Solutions for Boussinesq Equations using Homotopy Perturbation Padé Technique

Based on the homotopy perturbation method (HPM) and Padé approximants (PA), approximate and exact solutions are obtained for cubic Boussinesq and modified Boussinesq equations. The obtained solutions contain solitary waves, rational solutions. HPM is used for analytic treatment to those equations and PA for increasing the convergence region of the HPM analytical solution. The results reveal tha...

متن کامل

Generic properties of Padé approximants and Padé universal series

We establish properties concerning the distribution of poles of Padé approximants, which are generic in Baire category sense. We also investigate Padé universal series, an analog of classical universal series, where Taylor partial sums are replaced with Padé approximants. In particular, we complement previous studies on this subject by exhibiting dense or closed infinite dimensional linear subs...

متن کامل

Problema De Momentos De Stieltjes Y Convergencia De Aproximantes De Padé Para Funciones Meromorfas De Stieltjes

We obtain a result on convergence of Padé approximants for meromorphic functions of Stieltjes type. Connection of Padé approximants with Stieltjes moment problem plays a key role in the proof.

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2012